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激素对糖尿病与非糖尿病伴特发性面神经麻痹的疗效比较
作者:周艳霞 龙霞 李鹭江 
单位:广东省深圳市第二人民医院
关键词:糖尿病 面神经麻痹 激素 
分类号:
出版年·卷·期(页码):2011·39·第一期(5-9)
摘要:

目的 观察糖尿病(DM)患者与健康人伴的面神经麻痹对激素治疗的对照研究及电生理分析。方法 选择41例面神经麻痹患者,20例无DM史,21例有DM史,分别采用常规激素治疗、短期激素治疗、不用激素治疗三种方法,比较三种治疗方法的不同效果。结果不管是轻中度面瘫患者还是重度面瘫患者,健康人用激素治疗效果最优,对于DM患者,轻中度患者又用激素治疗效果比不用激素治疗者差,对于重度患者,用激素治疗与不用激素治疗,差别并没有显著性。DM组的神经传导速度(NCV)及瞬目反射(BR)的重度异常率均明显高于健康人。结论 对于DM伴发的面神经麻痹患者,不管病情轻重,尽量控制血糖在正常范围是基础,即使是重症患者,短期激素的使用也并不能改善患者的预后。

[Objective] To evaluate electrophysiological findings and comparative study with steroids treatment of acute peripheral facial palsy in diabetic and non-diabetic patients.[Methods] Selected 41 patients with peripheral facial paralysis, 20 patients with non-diabetic mellitus and 21 patients with diabetic mellitus ,were treated with conventional steroids therapy、short-term steroids therapy、without steroids therapy,compared the effects of three different treatment methods.[Results] Whether patients with mild to moderate or severe facial paralysis,non-diabetic group with steroids therapy is best。For patients with mild to moderate facial paralysis, diabetic group without hormone therapy is better than diabetic group with hormone therapy ; for severe patients, the two methods were not different. The severely sbnormal rate of the nerve conduction velocity and blink reflex in diabetic group were significantly higher than the one in non-diabetic group.[Conclusion] The facial palsy associated with diabetes patients, regardless of severity, control blood sugar in normal range as possible is the foundation.The serious facial paralysis associated with diabetes mellirus can be considered short-term steroids therapy. Even patients with severe facial paralysis, hormone therapy also does not improve the prognosis.

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