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乳腺分叶状肿瘤全数字化乳腺摄影表现与病理对照分析
作者:邱云 丁天一 刘万花 
单位:丹阳市人民医院
关键词:分叶状肿瘤 乳腺 全数字化乳腺摄影 病理 
分类号:
出版年·卷·期(页码):2011·39·第六期(631-634)
摘要:

目的 分析乳腺叶状肿瘤(phyllode tumor of the breast , PTB)的FFDM(Full-field digital mammography)表现,以期从FFDM角度提高对该病认识。方法 回顾性分析经手术病理证实25例PTB的FFDM表现及临床资料,并与病理学分级结果相对照。结果 (1)25例PTB中,病理学分级为良性、交界性及恶性的百分比分别为40%(10/25)、16%(4/25)、44%(11/25);(2) FFDM主要表现为分叶状肿块,占88.0%,其中浅分叶、深分叶及无分叶的百分比分别为28%(8/25)、60%(15/25)、12%(3/25);肿块边缘呈部分光整部分模糊为主,占64%;肿块最长径多大于3cm,占68%,但是小于3cm的8例中,恶性叶状肿瘤有6例,占75%;乳腺叶状肿瘤的异常血管显示率为68 %(17/25),其中良性、交界性及恶性的显示率分别为60% (6/10)、50.0% (2/4)及81.8% (9/11),最大径≤3 cm的PTB的异常血管显示率为62.5% (5/8),最大径>3 cm的PTB的异常血管显示率为70.6%(12/17);叶状肿瘤肿块伴钙化的发生率为24%(6/25),良性、交界性及恶性叶状肿瘤均可发生,以良性多见,多表现为粗大散在斑状钙化 ;叶状肿瘤FFDM表现与病理分级无统计学差异(p>0.05) (3) FFDM诊断与病理诊断符合率为68%。 结论 FFDM表现对PTB的诊断具有一定的指导意义。

Objective To study the Full-field digital mammography characteristics of the breast phyllode tumor(PTB) for enhancing the diagnosis of the disease. Methods Clinical manifestation and FFDM findings were retrospectively reviewed in twenty-five women confirmed by surgical pathology. Results (1) The histologic grades of all cases were respectively benign 40.0%(10/25), borderline 16.0%(4/25)and malignant 44.0%(11/25). (2) 88.0%(22/25)of cases showed lobulated mass in FFDM . The percentage of light leaf, deep leaf and without leaf were 28.0%(8/25), 60%(15/25) and 12.0%(3/25) respectively; 64% of cases manifasted part well-defined magin and part vague magin and 68% of tumor is larger than 3cm in diameter . 75.0%(6/8)lesions were malignant during tumors less than 3.0 cm in diameter;The abnormal blood vessel demonstration of PTB is 68.0%(17/25) and were 60% (6/10),50.0% (2/4) and 81.8% (9/11) in benign, borderline and malignant respectively, the demonstration rate of unusual blood vessel was 62.5% (5/8) during tumors less than 3.0 cm in diame and was 70.6%(12/17) during tumors larger than or equal to 3.0 cm in diameter; the calcification rate of PTB is 24%(6/25)and calcifications may be found in all grade PTB, but it is more ofen in benign cases. Most calcifications were large and coarse and some of them manifested pleomorphic calcification. All the differences between the FFDM findings and pathological grade of PTB had no significance(p>0.05). (3) The diagnositic coincidence rate of Full-field digital mammography and Pathology was 68%. Conclusion Several characteristic features of PTB were found in FFDM and clinical manifestation ,therefore FFDM had helpful value for the diagnosis of breast phyllode tumor.

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