国内空气消毒机和紫外线照射应用于手术室消毒的Meta分析-现代医学

国内空气消毒机和紫外线照射应用于手术室消毒的Meta分析

单位：中国医科大学附属第四医院

分类号：

出版年·卷·期（页码）：2013·41·第一期（32-34）

摘要：

目的：采用循证医学Meta分析方法评价国内空气消毒机和紫外线照射应用于手术室消毒的效果差异。方法：计算机检索万方、CNKI、维普和CBM等中文数据库，检索年限自建库至2012年6月，全面收集已发表的有关国内空气消毒机和紫外线照射消毒应用于手术室消毒的临床对照研究，由两位研究者分别独立提取数据，采用Review Manager 5.1.6和STATA 12.0软件进行Meta分析。结果：严格根据纳入和排除标准进行文献筛选，最终8个临床对照研究符合纳入标准。Meta分析结果表明：空气消毒机应用于手术室的消毒效果明显优于紫外线照射，前者消毒后空气中菌落数（SMD=-688.06，95%CI: -1330.39~-45.72，P=0.04）、细菌总量（OR=0.06，95%CI: 0.01~0.34，P=0.001）等均明显优于后者。结论：现有证据表明，手术室使用空气消毒机消毒效果明显优于紫外线照射，对减少患者手术感染有重要的临床意义，适用于手术室常规消毒。

Objective: Evaluation of efficacy between air sterilization machine and ultraviolet radiation in the air disinfection of operating room by conducting a meta-analysis. Methods: The CBM, Wanfang, VIP and CNKI databases were searched for all articles published up to June, 2012 that addressed air sterilization machine and ultraviolet radiation in the air disinfection of operating room. Statistical analyses were performed using RevMan 5.1.6 and STATA 12.0 softwares. Results: According to inclusion criteria, eight studies were included. Meta-analysis results showed that there were statistically significant differences between air sterilization machine and ultraviolet radiation in the number of bacteria (SMD=-688.06, 95%CI: -1330.39~-45.7, P=0.04) and total bacteria amount (OR=0.06, 95CI: 0.01~0.34, P=0.001). Conclusion: Results from the current meta-analysis suggested that the air sterilization machine is better than ultraviolet radiation in the air disinfection of operating room, and using air sterilization machine can decrease the rate of surgical infection.

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