Traditional Chinese medicine is a traditional Chinese medicine in China-specific drug，Widely used in the prevention and treatment of various diseases and has been for thousands of years. However, Traditional Chinese medicine complexity has become one of the important issues in its modernization process. In this context, traditional Chinese medicine fingerprint can effectively reflect the holistic and comprehensive role of the active ingredients of the medicinal plants; evaluation of the quality of medicinal plants from the whole upper body, thus chromatographic analysis technology has laid a good foundation for the study of traditional Chinese medicine fingerprint. In this paper, chromatographic analysis of the latest technology in the application and development prospects of traditional Chinese medicine fingerprint Review.