Objective: To enhance the level of diagnosis and treatment by discussing the features of onset of abdominal wall endometriosis and the efficacy of surgical treatment. Methods: Retrospective analysis was made on the clinical data of 27 patients. According to their surgical and pathological findings, all of them were confirmed as abdominal wall endometriosis patients. A focused analysis was made on the relationship between onset age, clinical symptoms and menstruation, as well as on the time of onset, number of nidus and the efficacy of surgical treatment. Results: The onset age of all 27 patients is between 24 to 43 years old. The average age of patients is 32.22 years old. The median age of patients is 32 years old. All patients have a history of cesarean section, and their nidus is located in the site of incision. 24 singular lesions were found in the site of incision (accounting for 88.89%). 3 patients suffered from lesions in two places. Most patients are aged between 30~39 years old (66.67%, 18/27). Comparing with patients of other ages, the difference is significant (p＜0.01). All patients went to hospital due to painful tumor in the site of incision. A close connection could be found between the clinical symptoms, the change in the size of tumor and the menstruation of 21 patients (77.78%). No significant connection could be found on 6 patients (22.22%). The difference is significant between the two groups (p＜0.01). Patients suffered from abdominal wall endometriosis 3~7 months after the surgery. The time of onset will change on different patients. But the morbidity is the highest (55.56%) on patients 2 years after their acceptance of surgery. A postoperative follow-up, which lasts for 6~18 months, was made on all patients. 1 patient suffered a relapse 4 months after the surgery. The morbidity is 3.7% (1/27). Conclusion: Abdominal wall endometriosis has typical manifestation. It is not difficult to make a preoperative diagnosis. Satisfactory short-term effect