[Abstract] Objective: To investigate and evaluate the application value of personalized discharge plans on patients with chronic obstructive pulmonary diseases. Methods:120 cases of patients with chronic obstructive pulmonary disease in our hospital were randomly divided into two groups by treatment methods: the experiment group (60 cases ) was treated with personalized discharge plans,and related plans treatment was given according to the personalized indexes of patients; the control group (60 cases ) was treated with routine nursing measures.The depression and exercise tolerance of two groups patients were compared. Results: The incidence of depression in the observation group patients was obviously higher than that of control group patients（P<0.05）, 6 min walking distance in the observation group patients was obviously more far than that of control group patients（P<0.05）. Conclusions: Individual hospital service applied to patients with chronic obstructive pulmonary disease patients can effectively improve the depression and exercise tolerance,it is worthy of further popularization and application.