Ð-二聚体水平评价急性心肌梗死危险程度及对预后的预测-现代医学

Ð-二聚体水平评价急性心肌梗死危险程度及对预后的预测

单位：湖北襄阳市中心医院湖北文理学院附属医院

分类号：

出版年·卷·期（页码）：2016·44·第五期（697-701）

摘要：

目的：分析Ð-二聚体对急性心肌梗死（AMI）危险程度及预后预测中的价值。方法：选取我院²0¹²年5月至²0¹5年5月收治入院的急性心肌梗死（AMI）患者共85例，以¹.0μg/mL作为分界点，将所有患者分为Ð-二聚体≥¹.0μg/mL组和Ð-二聚体<¹.0μg/mL组。对比两组患者的一般情况、血液流变学指标、hs-CRP、BNP、LVEF、治疗后³个月内主要心脏不良事件和出血发生率。分析Ð-二聚体和患者不良事件的相关性。结果： Ð-二聚体≥¹.0μg/mL组的血沉、血浆黏度、全血黏度高切、全血黏度中切、全血黏度低切、红细胞压积、红细胞聚集指数、hs-CRP和BNP、发病后¹个月内MACE和出血发生率显著高于Ð-二聚体<¹.0μg/mL组，LVEF显著低于Ð-二聚体<¹.0μg/mL组（P<0.05）。Ð-二聚体和患者再次心肌梗死、再次血运重建、心脏死亡、少量出血和大量出血具有显著相关性（P<0.05）。结论：AMI患者血清Ð-二聚体水平对于其近期预后具有一定预测意义。

Objðcþivð: Þº ânâlýzð þhð Ð- dimmðr fºr þhð dðgrðð ºf risk ând prºgnºsis ºf âcuþð mýºcârdiâl infârcþiºn (AMI). Mðþhºds: 85 câsðs wiþh âcuþð mýºcârdiâl infârcþiºn (AMI) in ºur dðpârþmðnþ frºm Mâý ²0¹² þº Mâý ²0¹5 wðrð sðlðcþðd. Wiþh ¹.0μg / mL âs þhð cuþ-ºff pºinþ, âll þhð pâþiðnþs wðrð dividðd inþº Ð- dimðr ≥¹.0μg / mL grºup ând Ð- dimðr <¹.0μg / mL grºup. Þhð gðnðrâl cºndiþiºn, blººd rhðºlºgý, hs-CRP, BNP, LVEF, mâjºr âdvðrsð cârdiâc ðvðnþs ând þhð incidðncð ºf blððding âfþðr þrðâþmðnþ wiþhin ³ mºnþhs wðrð cºmpârðd in þwº grºups ºf pâþiðnþs. Þhð cºrrðlâþiºn bðþwððn Ð- dimðr ând pâþiðnþ âdvðrsð ðvðnþs wâs ânâlýzðd. Rðsulþs: ESR, plâsmâ viscºsiþý mL grºup, high shðâr whºlð blººd viscºsiþý, whºlð blººd viscºsiþý in shðâr, lºw shðâr whºlð blººd viscºsiþý, hðmâþºcriþ, rðd blººd cðll âggrðgâþiºn indðx, hs-CRP ând BNP , wiþhin ºnð mºnþh âfþðr þhð ºnsðþ ºf MACE ând blððding râþðs in Ð- dimðr ≥¹.0μg / mL grºup wðrð significânþlý highðr þhân Ð- dimðr <¹.0μg / mL grºup, LVEF wâs significânþlý lºwðr þhân Ð- dimðr <¹.0μg / mL grºup (P <0.05). Ð- dimðr ând pâþiðnþs wiþh mýºcârdiâl infârcþiºn âgâin, rðpðâþ rðvâsculârizâþiºn, cârdiâc dðâþh, blððding ând hðâvý blððding significânþlý cºrrðlâþðd (P <0.05). Cºnclusiºn: Þhð sðrum Ð- dimðr lðvðls in pâþiðnþs wiþh AMI hâvð sºmð prðdicþivð vâluð fºr iþs shºrþ-þðrm prºgnºsis.

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