Objective: To explore the effect of hyperhomocysteine on cadiac remodling in patients with hypertensive. Methods: A total of 104 hypertensive patients admitted in our hospital from 2016-09 to 2017-03 were enrolled and divided into 2 groups:normal-Hcy group and high-Hcy group. LAD, LVDD, IVS, LVPW, RA of patients were measured using echocardiography, then LVM and LVMI was evaluated. Results: Compared to the normal-Hcy group, the high-Hcy group had higher level of LA(3.81±0.45 vs 3.57±0.38), LVED(4.84±0.27 vs 4.68±0.27), IVS (0.88±0.1 vs 0.82±0.09), LVPW(0.85±0.09 vs 0.8±0.07), LVW(163.77±36.88 vs 143.58±32.56), LVWI(95.54±25.3 vs 83.51±19.64), RV(2.03±0.2 vs 1.94±0.11).Conclusion: Blood level of homocysteine was positively related to cardiac remodeling in patients with hypertension.
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