Objective: To explore the relationship between atherosclerosis and HbAlc in people with normal blood glucose.Methods: One hundred and eight-four subjects with normal blood glucose who examined by CTA were enrolled in this study and were divided into different groups according to fasting blood glucose levels and CTA results.The contents of HbAlc, coronary artery Gensini scores and the degrees of coronary atherosclerosis were compared among the different groups.The correlation between HbAlc and coronary artery Gensini scores was analyzed. Results: The contents of HbAlc of normal blood glucose group were lower than those of limit blood glucose group in moderate and severe atherosclerosis groups(P<0.05). There was statistical significance in Gensini scores among coronary atherosclerosis groups in people with normal and limit blood glucose(P<0.05). The Gensini score in normal blood glucose group(47.21±3.69) was lower than that in limit blood glucose group(52.25±3.82) in severe atherosclerosis group(P<0.05). The proportion of normal coronary artery in normal blood glucose group(51.72%) was higher than that in limit blood glucose group(39.68%)(P<0.05). Through Rank sum test, there was statistical significance in degree of coronary atherosclerosis between normal blood glucose and limit blood glucose groups(P<0.05). The serum HbA1c level was positively correlated with coronary Gensini score(r=0.384,P< 0.001).Conclusion: Serum HbAlc level is positively correlated with the degree of coronary atherosclerosis, and it can participate in the development of coronary atherosclerosis.