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老年男性高血压患者中左室肥厚与代谢指标相关性的研究
作者:韩丽  段俊丽  杨玲  潘永瑜 
单位:上海交通大学医学院附属新华医院 老年医学科, 上海 200092
关键词:老年男性 高血压 左室肥厚 同型半胱氨酸 
分类号:R541.3
出版年·卷·期(页码):2017·36·第六期(781-784)
摘要:

目的:探讨老年男性高血压患者中,左室肥厚与同型半胱氨酸、血糖等代谢指标之间的关系。方法:收集119例患者,进行生化代谢指标、心脏彩色多普勒超声及24 h动态血压等检查,根据左室质量指数将患者分为左室肥厚组(n=46)和非左室肥厚组(n=73),分析两组的检查结果。结果:左室肥厚组的24 h平均收缩压、糖化血红蛋白、同型半胱氨酸均显著高于左室正常构型组(P<0.05),经多元线性逐步回归分析,24 h平均收缩压及同型半胱氨酸与左室质量指数相关。结论:老年高血压患者左室肥厚与多种因素有关,其中,高同型半胱氨酸对左室肥厚的影响独立于其他危险因素。

Objective: To explore the relationship between metabolic markers such as homocysteine, glucose and left ventricular hypertrophy (LVH) in elderly hypertensive males. Methods: 119 patients undertook blood tests, echocardiography and 24 hour ambulatory blood pressure monitoring, then were divided into left ventricular hypertrophy group (LVH) (n=46) and without left ventricular hypertrophy group (NLVH) (n=73). The general data, biochemical paremeters were analyzed. Results: In the LVH group, 24 hour average systolic blood pressure (24 h SBP), glycosylated hemoglobin and homocysteine were higher (P<0.05). Multiple linear stepwise regression analysis showed LVMI significantly correlated with 24 h SBP and homocysteine. Conculsion: LVH was associated with many factors in elderly patients. Hyperhomocysteine was an independent risk factor for LVH.

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