[1] MUGHAL W,DHINGRA R,KIRSHENBAUM L A.Striking a balance:autophagy,apoptosis,andnecrosis in a normal and failing heart[J].Curr Hypertens Rep,2012,14(6):540-547.
[2] METZSTEIN M M,STANFIELD G M,HORVITZ H R.Genetics of programmed cell death in C.elegans:past,present and future[J].Trends Genet,1998,14(10):410-416.
[3] GRANCARA S,OHKUBO S,ARTICO M,et al.Milestones and recent discoveries on cell death mediated by mitochondria and their inter actions with biologically active amines[J].Amino Acids.2016,48(10):2313-2326.
[4] RAO R V,NIAZI K,BREDESEN D E,et al.Coupling endoplasmic reticulum stress to the cell death program:a novel HSP90-independent role for the small chaperone protein p23[J].Cell Death Differ,2006,13(3):415-425.
[5] LUNA-VARGAS M P,CHIPUK J E.The deadly landscape of pro-apoptotic BCL-2 proteins in the outer mitochondrial membrane[J].FEBS J,2016,283(14):2676-2689.
[6] YUAN S,AKEY C W.Apoptosome structure,assembly,and procaspase activation[J].Structure.2013,21(4):501-515.
[7] BERNARDI P.The mitochondrial permeability transition pore:a mystery solved?[J].Front Physiol,2013,4(1):95.
[8] SABBAH H N.Targeting mitochondrial dysfunction in the treatment of heart failure[J].Expert Rev Cardiovasc Ther,2016,14(2):1-9.
[9] DEDKOVA E N,BlatterLA.Measuring mitochondrial function in intact cardiac myocytes[J].J Mol Cell Cardiol,2012,52(1):48-61.
[10] RENAULT T T,CHIPUK J E.Death upon a kiss:mitochondrial outer membrane composition and organelle communication govern sensitivity to BAK/BAX-dependent apoptosis[J].Chem Biol.2014,21(1):114-123.
[11] TSUJIMOTO Y,COSSMAN J,JAFFE E,et al.Involvement of the bcl-2 gene in human follicular lymphoma[J].Science,1985,228:1440-1443.
[12] SIDDIQUI WA,AHAD A,AHSAN H.The mystery of BCL2 family:Bcl-2 proteins and apoptosis:an update[J].Arch Toxicol,2015,89(3):289-317.
[13] EDWARDS A,GAVATHIOTIS E,LABELLE J,et al.Multimodal interaction with BCL-2 family proteins underlies the proapoptotic activity of PUMA BH3[J].Chem Biol,2013,20(7):888-902.
[14] LEE EF,DEWSON G,EVANGELISTA M,et al.The functional differences between pro-survival and pro-apoptotic B cell lymphoma 2(Bcl-2) proteins depend on structural differences in their Bcl-2 homology 3(BH3) domains[J].J Biol Chem,2014,289(52):36001-36017.
[15] DOERFLINGER M,GLAB J A,PUTHALAKATH H.BH3-only proteins:a 20-year stock-take[J].FEBS J,2015,282(6):1006-1016.
[16] CZABOTAR P E,LESSENE G,STRASSER A et al.Control of apoptosis by the BCL-2 protein family:implications for physiology and therapy[J].Nat Rev Mol Cell Biol,2014,15(1):49-63.
[17] SHAMAS-DIN A,KALE J,LEBER B,et al.Mechanisms of action of Bcl-2 family proteins[J].Cold Spring Harb Perspect Biol,2013,5(4):a008714.
[18] CHEN HC,KANAI M,INOUE-YAMAUCHI A,et al.An interconnected hierarchical model of cell death regulation by the BCL-2 family[J].Nat Cell Biol,2015,17(10):1270-1281.
[19] SHAMAS-DIN A,BINDNER S,ZHU W,et al.tBid undergoes multiple conformational changes at the membrane required for Bax activation[J].J Biol Chem,2013,288:22111-22127.
[20] TODT F,CAKIR Z,REICHENBACH F,et al.Differential retrotranslocation of mitochondrial Bax and Bak[J].EMBO J,2015,34:67-80.
[21] GOLDENTHAL M J.Mitochondrial involvement in myocyte death and heart failure[J].Heart Fail Rev,2016,21(2):137-155.
[22] KONSTANTINIDIS K,WHELAN R S,KITSIS R N.Mechanisms of cell death in heart disease[J].Arterioscler Thromb Vasc Biol.2012,32(7):1552-1562.
[23] MAYORGA M,BAHI N,BALLESTER M,et al.Bcl-2 is a key factor for cardiac fiborblast resistance to programmed cell death[J].J Biol Chem,2004,279(33):34882-34889.
[24] BROCHERIOU V,HAGEGE AA,OUBENAISSA A,et al.Cardiac functional improvement by a human Bcl-2 transgene in a mouse model of ischenmia/reperfusion injury[J].J Gene Med.2000,2(5):326-333.
[25] WEISLEDER N,TAFFET G E,CAPETANAKI Y.Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy[J].Proc Natl Acad Sci,2004,101:769-774.
[26] CHO G W,ALTAMIRANO F,HILL J A.Chronic heart failure:Ca(2+),catabolism,and catastrophic cell death[J].Biochim Biophys Acta,2016,1862(4):763-777.
[27] SCHELLENBERG B,WANG P,KDDBLE J A,et al.Bax exists in a dynamic equilibrium between the cytosol and mitochondria to control apoptotic priming[J].Mol Cell,2013,49:959-971.
[28] RENAULT T T,FLOROS K V,ELKHOLI R,et al.Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis[J].Mol Cell,2015,57(1):69-82.
[29] KORSMEYER S J,SHUTTER J R,VEIS D J,et al.Bcl-2/Bax:a rheostat that regulates an anti-oxidant pathway and cell death[J].Semin Cancer Biol.1993,4(6):327-332.
[30] JUNG F,WEILAND U,JOHNS R A,et al.Chronic hypoxia induces apoptosis in cardiac myocytes:a possible role for Bcl-2-like proteins[J].Biochem Biophys Res Commun,2001,286:419-425.
[31] LI Y,SONG P,ZHU Q,et al.Liguzinediol improved the heart function and inhibited myocardial cell apoptosis in rats with heart failure[J].Acta Pharmacol Sin,2014,35(10):1257-1264. |
