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胰岛素强化治疗对急诊脑梗死患者溶栓疗效的影响
作者:蒋召芹1  李广章2  张重阳1  穆永芳1  刘宇鹏1  聂亚冬1 
单位:1. 秦皇岛市第一医院 急诊科, 河北 秦皇岛 066000;
2. 秦皇岛市第一医院 骨科, 河北 秦皇岛 066000
关键词:脑梗死 溶栓治疗 血糖水平 治疗效果 
分类号:R743.3
出版年·卷·期(页码):2018·46·第七期(755-757)
摘要:

目的:分析胰岛素强化治疗对急诊脑梗死患者溶栓疗效的影响。方法:收集2016年7月至2017年9月100例在我院就诊的急性脑梗死患者,采用随机数字表法分为常规治疗组与胰岛素强化治疗组,每组50例。比较两组患者平均血糖水平、美国国立卫生研究院卒中量表(NHISS)评分、出血转化(HT)率、复发率及并发症的差异。结果:治疗后,胰岛素强化治疗组平均血糖较常规治疗组明显下降,NISHH评分、HT率、复发率及并发症发生率明显低于常规治疗组,差异均有统计学意义(P<0.01)。结论:胰岛素强化治疗能有效地改善脑梗死患者溶栓治疗后的神经功能,降低HT率、复发率和并发症风险。

Objective: To analyze the effect of insulin intensive treatment on thrombolytic efficacy in patients with acute cerebral infarction.Methods:A total of 100 patients with acute cerebral infarction treated in our hospital from July 2016 to September 2017 were randomly divided into the conventional treatment group and the insulin intensive treatment group, with 50 cases in each group.The mean blood glucose levels,National Institutes of Health Stroke Scale(NHISS)score,haemorrhage transformation(HT) rate,recurrence rate and complications were compared between the two groups.Results:After treatment, the average blood glucose level in the insulin intensive treatment group was significantly lower than that in the conventional treatment group. The NISHH score, HT rate, the recurrence rate and complication in the insulin intensive treatment group were significantly lower than those in the conventional treatment group,and the difference were statistically significant(P<0.01). Conclusion: Insulin intensive therapy can effectively improve the neurological function, decrease the HT rate and complications, and improve the therapeutic effect of cerebral infarction patients after thrombolytic therapy.

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