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布地奈德联合特布他林雾化吸入对小儿支原体肺炎的疗效及对肺功能的影响
作者:陈海英  乔娅 
单位:榆林市榆阳区人民医院 儿童重症医学科, 陕西 榆林 719000
关键词:布地奈德 特布他林 支原体肺炎 肺功能 小儿 
分类号:R725.6;R563.15
出版年·卷·期(页码):2018·46·第十期(1115-1118)
摘要:

目的:观察布地奈德联合特布他林雾化吸入对小儿支原体肺炎(MPP)的治疗效果以及对肺功能的影响。方法:选取180例MPP患儿,随机分为对照组和观察组各90例。对照组患儿给予基础治疗,观察组患儿在对照组治疗基础上采用布地奈德联合特布他林雾化吸入治疗。观察两组患儿治疗效果,记录临床症状改善时间,治疗前和治疗10 d检测用力肺活量(FVC)、最高呼气峰流速(PEF)和第1秒最大呼气容积(FEV1)。结果:观察组治疗总有效率为91.1%,显著高于对照组的78.9%(P<0.05);观察组患儿退热时间、咳嗽憋喘消失时间和干湿啰音消失时间显著短于对照组(P<0.05);治疗10 d后,两组患儿肺功能指标FVC、PEF和FEV1均有改善,观察组显著优于对照组(P<0.05)。结论:布地奈德联合特布他林雾化吸入治疗小儿MPP可提高整体疗效,改善临床症状,并可促进肺功能恢复。

Objective:To investigate the effect of budesonide combined with terbutaline inhalation on mycoplasma pneumonia (MPP) and pulmonary function in children. Methods:One hundred and eighty patients were selected as study subjects. All the patients were randomly divided into control group and observation group with 90 cases in each group. The control group received routine therapy, while the observation group received treatment of budesonide combined with terbutaline inhalation in addition to routine therapy. The therapeutic effect, time of clinical symptom improvement, forced vital capacity (FVC), peak expiratory flow (PEF) and forced expiratory volume in 1 s (FEV1) were observed and documented in the two groups. Results:The effective rate (91.1%) in the observation group was significantly higher than that (78.9%) in the control group (P<0.05). The time of defervescence, disappearance of cough, asthma and moist rales in the observation group was obviously less than that in the control group (P<0.05). The FVC, PEF and FEV1 were improved both in the control group and the observation group 10 days after treatment. The pulmonary function of observation group was significantly better than that of the control group (P<0.05). Conclusion:Budesonide combined with terbutaline inhalation can improve curative rate, clinical symptoms and pulmonary function in the treatment of children with MPP.

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