Objective:To explore the effect of dahuangzhechongwan pills combined with leuprorelin on endometriosis. Methods:123 cases of endometriosis patients afterlaparoscopy in our hospital were divided into the control group 1 (41 cases), control group 2 (41 cases) and observation group (41 cases). The control group 1 was treated with leuprorelin, control group 2 was treated with dahuangzhechongwan pills and the observation group was given dahuangzhechongwan pills and leuprorelin. The treatment time was 28 weeks. Before and 28 weeks after the treatment, the living quality scores (environmental scores, social scores, physical scores and life scores), sex hormone content (FSH, E2 and LH) and endometriosis markers content (MMP-3, CA-125, EMAb) were observed in the 3 groups. During the treatment, the adverse actions were observed. Results:After the treatment, the total effective rate was significantly higher in the observation group than in the control group (P<0.05). After the treatment, the environmental scores, social scores, physical scores and life scores were significantly higher in the observation group than the control group 1 and the control group 2 (P<0.05), while the levels of MMP-3, CA-125, EMAb, IgG, FSH, E2 and LH in the observation group were significantly lower than in the control group 1 and control group 2 (P<0.05). During the treatment, the rate of adverse reactions were similar in the 3 groups (P>0.05). Conclusion:Dahuangzhechongwan pills combined with leuprorelin in the treatment of endometriosis has a good clinical curative effect and safety, worthy of further study. |
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