[1] HALLIWELL B.Oxidative stress and neurodegeneration:where are we now?[J].J Neurochem,2006,97(6):1634-1658.
[2] YORIMITSU T,KLIONSKY D J.Autophagy:molecular machinery for self-eating[J].Cell Death Differ,2005,12(Suppl 2):1542-1552.
[3] DENGJEL J,ABELIOVICH H.Roles of mitophagy in cellular physiology and development[J].Cell Tissue Res,2017,367(1):95-109.
[4] RUB C,WILKENING A,VOOS W.Mitochondrial quality control by the Pink1/Parkin system[J].Cell Tissue Res,2017,367(1):111-123.
[5] ASHRAFI G,SCHWARZ T L.The pathways of mitophagy for quality control and clearance of mitochondria[J].Cell Death Differ,2013,20(1):31-42.
[6] MCWILLIAMS T G,MUQIT M M.PINK1 and Parkin:emerging themes in mitochondrial homeostasis[J].Curr Opin Cell Biol,2017,45:83-91.
[7] ONG S B,HAUSENLOY D J.Mitochondrial morphology and cardiovascular disease[J].Cardiovasc Res,2010,88(1):16-29.
[8] TANDLER B,HOPPEL C L,MEARS J A.Morphological pathways of mitochondrial division[J].Antioxidants(Basel),2018,7(2):30.
[9] 郑晴晴,赵佑山,常春康.线粒体形态变化对线粒体自噬水平的影响[J].诊断学理论与实践,2017,16(4):442-445.
[10] TWIG G,ELORZA A,MOLINA A J,et al.Fission and selective fusion govern mitochondrial segregation and elimination by autophagy[J].EMBO J,2008,27(2):433-446.
[11] RAMBOLD A S,KOSTELECKY B,ELIA N,et al.Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation[J].Proc Natl Acad Sci U S A,2011,108(25):10190-10195.
[12] GOMES L C,di BENEDETTO G,SCORRANO L.During autophagy mitochondria elongate,are spared from degradation and sustain cell viability[J].Nat Cell Biol,2011,13(5):589-598.
[13] KIM I,RODRIGUEZ-ENRIQUEZ S,LEMASTERS J J.Selective degradation of mitochondria by mitophagy[J].Arch Biochem Biophys,2007,462(2):245-253.
[14] WANG Y,NARTISS Y,STEIPE B,et al.ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy[J].Autophagy,2012,8(10):1462-1476.
[15] WEI X,QI Y,ZHANG X,et al.ROS act as an upstream signal to mediate cadmium-induced mitophagy in mouse brain[J].Neurotoxicology,2015,46:19-24.
[16] KOBAYASHI S,LIANG Q.Autophagy and mitophagy in diabetic cardiomyopathy[J].Biochim Biophys Acta,2015,1852(2):252-261.
[17] SACKS J,MULYA A,FEALY C E,et al.Effect of Roux-en-Y gastric bypass on liver mitochondrial dynamics in a rat model of obesity[J].Physiol Rep,2018,6(4):e13600.
[18] YOULE R J,NARENDRA D P.Mechanisms of mitophagy[J].Nat Rev Mol Cell Biol,2011,12(1):9-14.
[19] NUNNARI J,SUOMALAINEN A.Mitochondria:in sickness and in health[J].Cell,2012,148(6):1145-1159.
[20] YAMANO K,YOULE R J.PINK1 is degraded through the N-end rule pathway[J].Autophagy,2013,9(11):1758-1769.
[21] LAZAROU M,JIN S M,KANE L A,et al.Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin[J].Developmental Cell,2012,22(2):320-333.
[22] NARENDRA D P,JIN S M,TANAKA A,et al.PINK1 is selectively stabilized on impaired mitochondria to activate Parkin[J].PLoS Biol,2010,8(1):e1000298.
[23] JIN S M,YOULE R J.PINK1-and Parkin-mediated mitophagy at a glance[J].J Cell Sci,2012,125(Pt 4):795-799.
[24] KOYANO F,OKATSU K,KOSAKO H,et al.Ubiquitin is phosphorylated by PINK1 to activate parkin[J].Nature,2014,510(7503):162-166.
[25] EIYAMA A,OKAMOTO K.PINK1/Parkin-mediated mitophagy in mammalian cells[J].Curr Opin Cell Biol,2015,33:95-101.
[26] WEI H,LIU L,CHEN Q.Selective removal of mitochondria via mitophagy:distinct pathways for different mitochondrial stresses[J].Biochim Biophys Acta,2015,1853(10 Pt B):2784-2790.
[27] DURCAN T M,FON E A.The three ‘P’ s of mitophagy:PARKIN,PINK1,and post-translational modifications[J].Genes Dev,2015,29(10):989-999.
[28] BENDER A,KRISHNAN K J,MORRIS C M,et al.High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease[R].Nat Genet,2006,38(5):515-517.
[29] PARK J,LEE S B,LEE S,et al.Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin[J].Nature,2006,441(7097):1157-1161.
[30] SCARFFE L A,STEVENS D A,DAWSON V L,et al.Parkin and PINK1:much more than mitophagy[J].Trends Neurosci,2014,37(6):315-324.
[31] MARTELLA G,MADEO G,MALTESE M,et al.Exposure to low-dose rotenone precipitates synaptic plasticity alterations in PINK1 heterozygous knockout mice[J].Neurobiol Dis,2016,91:21-36.
[32] HAQUE M E,MOUNT M P,SAFARPOUR F,et al.Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)and can be rescued by autosomal recessive Parkinson disease genes,Parkin or DJ-1[J].J Biol Chem,2012,287(27):23162-23170.
[33] GEGG M E,COOPER J M,CHAU K Y,et al.Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy[J].Hum Mol Genet,2010,19(24):4861-4870.
[34] POOLE A C,THOMAS R E,ANDREWS L A,et al.The PINK1/Parkin pathway regulates mitochondrial morphology[J].Proc Natl Acad Sci U S A,2008,105(5):1638-1643.
[35] MIZUMURA K,CLOONAN S M,NAKAHIRA K,et al.Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD[J].J Clin Invest,2014,124(9):3987-4003.
[36] SIDDALL H K,YELLON D M,ONG S B,et al.Loss of PINK1 increases the heart's vulnerability to ischemia-reperfusion injury[J].PLoS One,2013,8(4):e62400.
[37] KUBLI D A,ZHANG X,LEE Y,et al.Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction[J].J Biol Chem,2013,288(2):915-926.
[38] WILLIAMS J A,DING W X.Targeting Pink1-Parkin-mediated mitophagy for treating liver injury[J].Pharmacol Res,2015,102:264-269. |