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双源CT测量左心房功能参数在评估冠状动脉狭窄情况和左心室功能中的价值
作者:倪其鸣  虞凌明  焦静 
单位:上海市胸科医院 放射科, 上海 200030
关键词:双源CT 冠状动脉狭窄 左心功能 诊断价值 
分类号:R814.42;R54
出版年·卷·期(页码):2019·38·第十一期(1383-1386)
摘要:

目的:探讨双源CT测量左心房功能参数在评估冠状动脉狭窄情况和左心室功能中的价值。方法:选择2017年1月至2018年4月在本院经冠状动脉造影(DSA)检查证实为冠状动脉狭窄的182例患者为研究对象,依据动脉狭窄程度分为轻度狭窄组(42例)、中度狭窄组(56例)、重度狭窄组(48例)以及闭塞组(36例),测量每组患者左心室舒张容积(ESV)、收缩容积(EDV)、射血分数(EF)、每搏输出量(SV)和心肌质量(MM),并进行组间比较,同时对冠状动脉狭窄程度与左心房功能指标的关系进行评价。结果:轻度狭窄组和中度狭窄组间EF、ESV比较差异无统计学意义(P>0.05)。4组EDV、SV及MM比较差异具有统计学意义;随着冠状动脉狭窄程度的加重,EDV和MM显著升高,呈正相关(r值分别为0.40、0.46,均P<0.05);SV显著降低,呈负相关(r=-0.42,P<0.05)。双源CT测量与DSA检查在诊断冠状动脉狭窄方面具有较好一致性,双源CT测量的特异度、灵敏度和准确率分别为96.1%、90.6%和97.0%。结论:冠状动脉狭窄程度与左心室功能具有良好相关性,双源CT测量左心房功能参数评估冠状动脉狭窄及左心室功能准确、可靠,值得在临床进一步应用。

Objective: To investigate the value of dual-source CT measurement of left atrial function parameters in assessing coronary stenosis and left ventricular function. Methods: From January 2017 to April 2018, 182 patients with coronary artery stenosis confirmed by digital subtraction angiography (DSA) in our hospital were enrolled. According to the degree of arterial stenosis, the patients were divided into mild stenosis group (42 cases), moderate stenosis group (56 cases), severe stenosis group (48 cases), and the occlusion group (36 cases). The left atrial end-systolic volume (ESV), diastolic volume (EDV), ejection fraction (EF), stroke volume (SV) and myocardial mass (MM) were measured and compared in the four groups, and the relationship between coronary artery stenosis and left atrial function was evaluated. Results: There was no significant difference in EF and ESV between the mild stenosis group and the moderate stenosis group (P>0.05). The difference of EDV, SV and MM in the four groups was statistically significant. With the severity of coronary artery stenosis, the EDV and MM were significantly increased, positively correlated (r=0.40, 0.46, P<0.05), and SV was significantly decreased, negatively correlated (r=-0.42, P<0.05); The dual-source CT measurement and DSA examination in the diagnosis of coronary artery arterial stenosis had a good consistency. The specificity, sensitivity and accuracy of dual-source CT measurements were 96.1%, 90.6% and 97.0%, respectively. Conclusion: Coronary artery stenosis has a good correlation with left ventricular function. Dual-source CT measurement of left atrial function parameters for coronary artery stenosis and left ventricular function is accurate and reliable, which is worthy of further clinical application.

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