Objective: to analyze the effect of Jiannao granule on patients with posterior circulation ischemia and the changes of cerebral blood flow in patients with carotid artery plaque. Methods: The clinical data of 104 patients with posterior circulation ischemia admitted to our hospital from May 2017 to August 2018 were selected for analysis. The patients were divided into control group, who received conventional treatment, andobservation group, who were treated with Jiannao granule on top of conventional treatment. The clinical efficacy of the two groups was analyzed after treatment. Results: The difference of carotid plaque between the two groups was not statistically significant (P> 0.05). The size of the plaque, the thickness of the plaque and the media thickness of the media in the treated group were lower than that of the control group (P>0.05). The levels of ET-1, TM, vWF, PDGF-BB, TXB2, GMP-140 and LPA in the observation group were lower than that of the control group (P>0.05). The peak blood flow velocity (Vs), mean blood flow velocity (Vm) and mean blood flow velocity (Vm) of the bilateral vertebral artery and basilar artery after treatment in the observation group were higher than that of the control group (P<0.05). Conclusion: After the treatment of cerebral ischemia, jiannao granule can reduce the thickness of plaque and improve the level of cerebral blood flow. |
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