目的：探究心电图非特异性ST段改变与成人高血压控制水平之间的相关性。方法：选取2012年2月至2015年6月在我院确诊为原发性高血压的486例成年患者作为研究对象，根据患者ST-T段情况分为观察组（280例）和对照组（206例），观察组患者存在非特异性ST-T段改变，对照组患者ST-T段正常。对两组患者随访观察3年，分析两组患者血压及相关指标变化。结果：观察组患者年龄、糖尿病占比均显著高于对照组，差异具有统计学意义（P<0.05）；两组成员吸烟以及饮酒情况差异具有统计学意义（P<0.05）。观察组患者总胆固醇（TC）、空腹血糖（FBG）、维生素B12均显著高于对照组，差异具有统计学意义（P<0.05）。两组患者基线收缩压差异无统计学意义（P>0.05），治疗后观察组患者收缩压下降和舒张压下降均显著低于对照组，差异具有统计学意义（P<0.05）。多重线性回归分析显示，调整性别、基线血压等相关影响因素后，非特异性ST-T段改变与未改变相比较，收缩压少下降1.42 mmHg，舒张压少下降0.49 mmHg，差异均具有统计学意义（P<0.05）。COX回归分析显示，非特异性ST-T段改变患者血压控制不达标风险高于未改变患者（RR=1.3，P<0.05）。结论：高血压患者中非特异性ST-T段改变较为多见，多因素回归分析显示非特异性ST-T改变是患者血压控制不达标的独立危险因素，临床上须更加重视该类患者。

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