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肠内营养性腹泻与肠壁通透性相关性研究进展
作者:王海翔1  王志国2  陈浩3  徐海1  严锋1  程文芳4  焦健华4 
单位:1. 南京中医药大学附属中西医结合医院/江苏省中医药研究院 老年科, 江苏 南京 210028;
2. 南京中医药大学附属中西医结合医院/江苏省中医药研究院 检验科, 江苏 南京 210028;
3. 南京中医药大学附属中西医结合医院/江苏省中医药研究院 重症医学科, 江苏 南京 210028;
关键词:肠内营养性腹泻 腹泻病理 肠壁通透性 综述 
分类号:R459.3
出版年·卷·期(页码):2020·39·第六期(791-795)
摘要:

临床上很多患者需要肠内营养支持治疗,然而腹泻一直是困扰临床治疗中最常见的不良反应,不仅导致患者延迟治疗,甚至需要终止肠内营养支持,影响患者康复与预后。近年来发现越来越多的研究强调肠黏膜屏障及肠道通透性对健康和疾病的重要作用。作者就黏膜屏障及其在疾病预防和治疗中的作用进行论述,并提出肠壁通透性"阈值"降低可能是导致肠内营养性腹泻原因之一,为进一步治疗肠内营养性腹泻提供可借鉴的方法。

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