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外泌体与卵巢相关疾病的研究进展
作者:孙寒香  高玉平 
单位:上海交通大学医学院附属新华医院 妇产科, 上海 200082
关键词:外泌体 卵巢 研究进展 
分类号:R711.75
出版年·卷·期(页码):2020·39·第八期(1080-1086)
摘要:

卵巢疾病对女性的身体健康有着严重的危害,很多卵巢相关疾病患者在确诊时已经处于疾病进展期,尤其是卵巢恶性肿瘤。同时对卵巢相关疾病进行治疗也十分困难,并且预后也存在反复复发的情况。外泌体是由多细胞囊泡体和细胞膜融合之后形成的膜性囊泡。外泌体自身可作为信息交流以及细胞间交流的工具,参与细胞间的通讯,把它们的分子运送到特定细胞中。同时外泌体参与多种生理和病理过程,包括癌的发生、免疫调节、蛋白质的转运、血管生成和转移等。本文对外泌体和卵巢相关疾病进行综述,同时分享了外泌体与卵巢相关疾病的研究进展。

Ovarian disease is a serious harm to the health of women. Many patients with ovarian-related diseases are already in the advanced stage of disease, especially malignant ovarian tumors. At the same time, it is very difficult to treat ovarian-related diseases, and the prognosis is recurrent. Exocrine is a membranous vesicle formed by the fusion of multicellular vesicles and cell membrane. Exocrine itself can be used as a tool for information communication and cell-to-cell communication, participating in cell-to-cell communication and transporting their molecules to specific cells. Exocrine is involved in a variety of physiological and pathological processes, including carcinogenesis, immunomodulation, and protein transfer, transport, angiogenesis and metastasis. In this paper, the exocrine and ovarian related diseases were reviewed, and the research progress of exocrine and ovarian related diseases was also shared.

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