[1] LEEMANS C R,BRAAKHUIS B J M,BRAKENHOFF R H.The molecular biology of head and neck cancer[J].Nat Rev Cancer,2011,11(1):9-22.
[2] VIGNESWARAN N,WILLIANMS M D.Epidemiologic trends in head and neck cancer and aids in diagnosis[J].Oral Maxillofac Surg Clin North Am,2014,26(2):123-141.
[3] BROWNSON R C,CHANG J C.Exposure to alcohol and tobacco and the risk of laryngeal cancer[J].Arch Environ Health,1987,42(4):192-196.
[4] GILLISON M L.Human papillomavirus-associated head and neck cancer is a distinct epidemiologic,clinical,and molecular entity[J].Semin Oncol,2004,31(6):744-754.
[5] LUNT S Y,VANDER HEIDEN M G.Aerobic glycolysis:meeting the metabolic requirements of cell proliferation[J].Annu Rev Cell Dev Biol,2011,27(1):441-464.
[6] TENNANT D A,DURAN R V,GOTTLIEB E.Targeting metabolic transformation for cancer therapy[J].Nat Rev Cancer,2010,10(4):267-277.
[7] COELHO R G,CAZARIN J M,CAVALCANTI DE ALBUQUERQUE J P,et al.Differential glycolytic profile and Warburg effect in papillary thyroid carcinoma cell lines[J].Oncol Rep,2016,36(6):3673-3681.
[8] PAYEN V L,PORPORATO P E,BASELET B,et al.Metabolic changes associated with tumor metastasis,part 1:tumor pH,glycolysis and the pentose phosphate pathway[J].Cell Mol Life Sci,2015,73(7):1333-1348.
[9] BRAND K.Aerobic glycolysis by proliferating cells:protection against oxidative stress at the expense of energy yield[J].J Bioenerg Biomember,1997,29(4):355-364.
[10] WINTER S C,SHAH K A,HAN C,et al.The relation between hypoxia-inducible factor(HIF)-1α and HIF-2α expression with anemia and outcome in surgically treated head and neck cancer[J].Cancer,2006,107(4):757-766.
[11] ZHU G,PENG F,GONG W,et al.Hypoxia promotes migration/invasion and glycolysis in head and neck squamous cell carcinoma via an HIF-1α-MTDH loop[J].Oncol Rep,2017,38(5):2893-2900.
[12] DIBBLE E H,LARA A C,TRUONG M T,et al.18F-FDG metabolic tumor volume and total glycolytic activity of oral cavity and oropharyngeal squamous cell cancer:adding value to clinical staging[J].J Nucl Med,2012,53(5):709-715.
[13] CHEN G,ZHANG Y,LIANG J,et al.Deregulation of hexokinase Ⅱ is associated with glycolysis,autophagy,and the epithelial-mesenchymal transition in tongue squamous cell carcinoma under hypoxia[J].Biomed Res Int,2018,2018:1-15.
[14] CHEN J,ZHANG S,LI Y,et al.Hexokinase 2 overexpression promotes the proliferation and survival of laryngeal squamous cell carcinoma[J].Tumour Biol,2014,35(4):3743-3753.
[15] KNOWLES L M,STABILE L P,EGLOFF A M,et al.HGF and c-Met participate in paracrine tumorigenic pathways in head and neck squamous cell cancer[J].Clin Cancer Res,2009,15(11):3740-3750.
[16] 于丽,陈向军,董学会,等.乳酸及乳酸清除率对烧伤休克患者预后的预测价值[J].现代医学,2020,48(2):167-171.
[17] HIRSCHHAEUSER F,SATTLER U G,MUELLER-KLIESER W.Lactate:A metabolic key player in cancer[J].Cancer Res,2011,71(22):6921-6925.
[18] BECKERT S,FARRAHI F,ASLAM R S,et al.Lactate stimulates endothelial cell migration[J].Wound Repair Regen,2006,14(3):321-324.
[19] DHUP S,DADHICH R K,PORPORATO P E,et al.Multiple biological activities of lactic acid in cancer:influences on tumor growth,angiogenesis and metastasis[J].Current Pharmaceutical Design,2012,18(10):1319-1330.
[20] WARBURG O.On the origin of cancer Cells[J].Science,1956,123(3191):309-314.
[21] SHIDARA Y,YAMAGATA K,KANAMOI T,et al.Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis[J].Cancer Res,2005,65(5):1655-1663.
[22] SANCHEZ-CESPEDES M,PARRELLA P,NOMOTO S,et al.Identification of a mononucleotide repeat as a major target for mitochondrial DNA alteration in human tumors[J].Cancer Res,2001,61(19):7015-7019.
[23] FLISS M S,USADEL H,CABALLERO O L,et al.Facile detection of mitochondrial DNA mutations in tumors and bodily fluids[J].Science,2000,287(5460):2017-2019.
[24] KIM MM,CLINGER J D,MASAYESVA B G,et al.Mitochondrial DNA quantity increases with histophatologic grade in premalignant and malignant head and neck lesions[J].Clin Cancer Res,2004,10(24):8512-8515.
[25] MITHANI S K,TAUBE J M,ZHOU S,et al.Mitochondrial mutations are a late event in the progression of head and neck squamous cell cancer[J].Clin Cancer Res,2007,13(15 Pt 1):4331-4335.
[26] HERZIG S,SHAW R J.AMPK:guardian of metabolism and mitochondrial homeostasis[J].Nat Rev Mol Cell Biol,2018,19(2):121-135.
[27] HOU C H,CHIANG Y C,FONG Y C,et al.WISP-1 increases MMP-2 expression and cell motility in human chondrosarcoma cells[J].Biochem Pharmacol,2011,81(11):1286-1295.
[28] OBAYASHI M,YOSHIDA M,TSUNEMATSU T,et al.microRNA-203 suppresses invasion and epithelial-mesenchymal transition induction via targeting NUAK1 in head and neck cancer[J].Oncotarget,2016,7(7):8223-8239.
[29] SUR S,NAKANISHI H,FLACEN C,et al.Inhibition of the key metabolic pathways,glycolysis and lipogenesis,of oral cancer by bitter melon extract[J].Cell Commun Signal,2019,17(1):131.
[30] 刘强,木拉提·热夏提,拜合提亚·阿扎提,等.顺铂诱导自噬和MAPK信号调控前列腺癌细胞耐药的机制研究[J].现代医学,2018,46(12):1325-1331.
[31] YU W,CHEN Y,PUTLURI N,et al.Acquisition of cisplatin resistance shifts head and neck squamous cell carcinoma metabolism toward neutralization of oxidative stress[J].Cancers(Basel),2020,12(6):1670.
[32] COSTANTINI P,JACOTOT E,DECAUDIN D,et al.Mitochondrion as a novel target of anticancer chemotherapy[J].J Nati Cancer Inst,2000,92(13):1042-1053.
[33] FRIGERIO F,CASIMIR M,CAROBBIO S,et al.Tissue specificity of mitochondrial glutamate pathways and the control of metabolic homeostasis[J].Biochim Biophy Acta,2008,1777(7-8):965-972.
[34] OKAZAKI S,UMENE K,YAMASAKI J,et al.Glutaminolysis-related genes determine sensitivity to xCT-targeted therapy in head and neck squamous cell carcinoma[J].Cancer Sci,2019,110(11):3453-3463.
[35] ZHANG G,FU J,SU Y,et al.Opposite effects of garcinol on tumor energy metabolism in oral squamous cell carcinoma cells[J].Nutr Cancer,2019,71(8):1403-1411.
[36] YANG J G,WANG W M,XIA H F,et al.Lymphotoxin-α promotes tumor angiogenesis in HNSCC by modulating glycolysis in a PFKFB3-dependent manner[J].Int J Cancer.2019,145(5):1358-1370. |
