Objective:To investigate the correlation between local recurrence and surgical margins after vertical partial laryngectomy for T1 glottic squamous cell carcinoma.Methods: The clinical data of 120 patients with laryngeal cancer who underwent a modified vertical partial laryngectomy admitted to our hospital from February 2013 to February 2015 were retrospectively analyzed. All patients were followed up for at least 5 years after discharge, depending on the existence of local recurrence was divided into local recurrence group (n=8) and non-recurrence group (n=112).Their surgical margins, pathological results, tumor diameters and invasion depths were recorded and compared between the two groups. Results:The margin distance (PLSM), the ratio of edge distance to upper and lower diameter (PLSM/ULD), the ratio of edge distance to inner and outer diameter(PLSM/IED), the ratio of edge distance to average diameter (PLSM/AD) and the shortest edge distance were significantly lower than those of non-recurrence group, the difference was statistically significant (P<0.05). And the pathological results showed that in recurrent group there were 6 patients with tumor margin <5 mm, 2 patients with tumor margin ≥ 5 mm; in non-recurrence group there were 10 patients with tumor margin <5 mm, 102 patients with tumor margin ≥ 5 mm, difference was statistically significant (P<0.001). During postoperative follow-up, There was no significant difference in the total overall survival of 3 and 5 years between the two groups (P>0.05).Conclusion:The lower PLSM has an important effect on the local recurrence after vertical partial laryngectomy of T1 glottic squamous cell carcinoma, and the margin of the surgical margin during vertical partial laryngectomy should not exceed 5 mm.
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