Objective:To investigate the effect of nutritional pre-rehabilitation on patients with esophageal cancer during radiotherapy and concurrent chemoradiotherapy. Methods: 102 patients with esophageal cancer who were at risk of malnutrition were selected from the radiotherapy department of our hospital from January 2017 to December 2019. They were randomly divided into the control group and the study group, with 51cases in each group. The control group performed a traditional diet program, and the study group performed a nutritional pre-rehabilitation program with ansuline as a support. We compared the nutritional holistic assessment(PG-SGA), nutritional index detection(BMI, ALB, PA, TP, TLC level), complications and life(KPS) of the two groups at the beginning of radiotherapy or the beginning or end of concurrent radiochemotherapy. Results: At the end of radiotherapy or concurrent radiochemotherapy, the PG-SGA scores and nutritional indicators of the study group were distinctly different from those of the control group. We found that the PG-SGA scores of the study group was markedly lower than control group when the patients finished the radiotherapy or concurrent radiochemotherapy,and the difference was statistically significant(t=12.132, P<0.001). The BMI, ALB, PA, TP, and TLC levels of the control group after the end of radiotherapy or concurrent radiochemotherapy were significantly lower than those of the study group (P<0.05). The incidence of complications after treatment in the study group(9.80%) was significantly lower than that in the control group(25.49%) (χ2=4.317, P=0.038).The difference of the KPS scores between the two groups after radiotherapy or concurrent radiochemotherapy. The KPS scores of the study group after radiotherapy or concurrent radiochemotherapy were evidently higher than those of the control group(t=-12.17, P<0.001). Conclusion: The use of nutritional pre-rehabilitation during radiotherapy and concurrent chemoradiotherapy in patients with esophageal cancer could obviously improve the malnutrition and indicators of patients, reduce the complications of treatment and optimize the quality of life.
 施靖华.肿瘤病人的营养支持[J].国外医学肿瘤学分册, 2020,14(4):219-221.
 付佳,唐磊,李子禹,等.CT区分Siewert Ⅱ型食管胃结合部腺癌cT3与cT4a:国际抗癌联盟/美国癌症联合委员会(UICC/AJCC)第8版分期与国际胃癌协会(IGCA)第4版分期对照研究[J].中华胃肠外科杂志,2018,21(9):1013-1018.