止血带在手术救治中具有十分重要的作用。止血带的使用为医生给患者进行手术提供了清晰的手术视野，降低了患者失血损失。然而，止血带的使用也给患者造成了疼痛等并发症，严重影响了患者的治疗效果和感受。如何有效地发挥止血带功能，预防和规避止血带疼痛风险成为止血带研究的主要方向。本文阐述止血带疼痛的机制，综述预防止血带疼痛的相关措施，包括止血带疼痛的物理性使用优化以及化学药物添加两类预防对策，展望预防止血带疼痛在未来的发展前景和方向，以期为止血带的疼痛预防研究提供理论指导。

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