Objective: To analyze the effectiveness and safety of transurethral plasmakinetic enucleation of prostate(PKEP) combined with plasmakinetic resection of prostate(PKRP) in the treatment of benign prostatic hyperplasia(BPH). Methods: 71 patients with BPH in the hospital were selected and divided into control group(36 cases) and observation group(35 cases) by the simple random grouping method of random number table according to single blind method. The control group was given PKRP, and the observation group was given PKEP combined with PKRP. Perioperative indicators and occurrence of perioperative complications were recorded in the two groups. Prostate volume, International Prostate Symptom Score(IPSS), BPH Quality of Life Scale(BPHQLS) score and urodynamics [post-voiding residual(PVR), maximum urinary flow rate(Qmax)] were compared before surgery and at 3 months after surgery. Surgical learning curve was drawn in observation group to analyze the number of surgical cases required for surgical stabilization, and Pearson correlation analysis was applied to evaluate the correlation between the number of surgical cases and surgical time. Results: There were no statistical differences in surgical time and perioperative complications between the two groups(P>0.05). Intraoperative blood loss was less(P<0.05), postoperative bladder irrigation time, postoperative catheter removal time and postoperative hospital stay were shorter(P<0.05) and the weight of removed tissue was heavier(P<0.05) in observation group compared to control group. At 3 months after surgery, prostate volume, IPSS and PVR of the two groups were reduced compared with those before surgery(P<0.05), and the changes in observation group were greater than those in control group(P<0.05). BPHQLS score and Qmax of the two groups were significantly enhanced compared with those before surgery(P<0.05), and the changes were greater in observation group(P<0.05). Surgical learning curve of observation group showed that with the increase of the number of surgical cases, the surgical time was gradually shortened. After 20 cases, surgical time stabilized and the number of surgical cases was negatively correlated with surgical time(r=-0.968, P<0.001). Conclusion: The combination of PKEP and PKRP are effective and safe in treating BPH, and their learning curve of surgery are not long. They are suitable for popularization and application in primary medical institutions. |
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