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基于肠道微生物疗法用于血脂异常治疗的研究现状
作者:张奕雯1  骆杨平2 
单位:1. 湖南师范大学附属第一医院 心血管内科, 湖南 长沙 410000;
2. 湖南省人民医院 心血管内科, 湖南 长沙 410000
关键词:肠道微生物 脂质代谢 血脂异常 心血管疾病 三甲胺-N-氧化物 综述 
分类号:R589.2;R459.3;Q939.93
出版年·卷·期(页码):2022·50·第五期(660-663)
摘要:

近年来,肠道微生物与宿主的相互作用得到越来越多的关注。肠道微生物在人类健康和疾病中起着重要作用,其中肠道微生物通过其自身或相互作用的代谢产物,对调节脂质代谢具有重要影响。本综述重点介绍了肠道微生物与宿主脂质代谢的相关性,三甲胺-N-氧化物、短链脂肪酸、胆汁酸等肠道微生物代谢产物对血脂水平的影响,并着重探讨肠道微生物疗法,包括饮食调节、益生菌和益生元、抗生素、粪便微生物群移植、微生物酶抑制治疗对脂质代谢的调节作用,期待为血脂异常的治疗提供参考。

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