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Septin9基因甲基化在胃癌诊断中的研究进展
作者:张祥  季雪梅 
单位:包头医学院包头市中心医院 消化内科, 内蒙古 包头 014040
关键词:胃癌 Septin9基因甲基化 危险因素 
分类号:R735
出版年·卷·期(页码):2023·51·第七期(1029-1032)
摘要:

胃癌作为全球最常见的恶性肿瘤之一,其不仅严重威胁患者的身心健康,而且给全球带来沉重的医疗卫生经济负担。近年来,我国随着各项预防措施的实施使得胃癌的发病率有所下降,但患者的预后仍不容乐观。虽然目前已经发现多种生物学标志物可以用于胃癌的辅助性诊断、预后评估以及疾病的治疗效果监测,但它们单独使用因为灵敏度和特异度较低而始终无法达到令人满意的效果。Stptin9是目前肿瘤领域的研究热点,其甲基化异常可能会影响多种癌症的发生发展过程。本文就胃癌发生相关的危险因素以及Stptin9甲基化检测在胃癌诊断中的应用研究进展作出综述。

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