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内侧支撑钢板结合空心钉治疗青壮年PauwelsⅢ型股骨颈骨折效果的Meta分析
作者:张伟  陈宇浩  吴沼锋  李杭  王健  赵继军 
单位:南京医科大学附属无锡人民医院 骨科, 江苏 无锡 214023
关键词:内侧支撑钢板 空心钉 股骨颈骨折 PauwelsⅢ型 Meta分析 
分类号:R683.42; R687.3
出版年·卷·期(页码):2024·52·第二期(239-248)
摘要:

目的:通过Meta分析比较内侧支撑钢板结合三枚空心钉与单纯三枚空心钉固定治疗青壮年PauwelsⅢ型股骨颈骨折的疗效。方法:检索知网、万方、维普、PubMed、Cochrane library、Web of Science(WOS)等数据库关于内侧支撑钢板结合三枚空心钉与单纯三枚空心钉治疗PauwelsⅢ型股骨颈骨折相关随机对照试验、队列研究等文献,检索年限为建库至2023年6月。分别由两名人员独立依据制定的纳入标准进行筛选、质量评价、数据提取等工作,最后应用Stata 14、17进行Meta分析。结果:最终纳入文献20篇,共纳入1 294例患者。Meta分析显示,内侧支撑钢板结合三枚空心钉组的手术时间长于单纯三枚空心钉组(MD=26.52,95%CI 20.99~31.50,P<0.001)、术中出血量多于单纯三枚空心钉组(MD=89.68,95%CI 70.95~107.42,P<0.001),复位质量为可(RR=0.32, 95%CI 0.17~0.58,P<0.001)及差(RR=0.17, 95%CI 0.06~0.45,P<0.001)均差于单纯三枚空心钉组;内侧支撑钢板结合三枚空心钉组的骨折愈合时间(MD=-1.05,95%CI-1.34~-0.67,P<0.001)、复位质量为优(RR=1.57, 95%CI 1.35~1.83,P<0.001)、术后并发症总数(RR=0.31, 95%CI 0.24~0.40,P<0.001)、股骨头坏死(RR=0.43, 95%CI 0.08~1.80,P<0.001)、骨折不愈合(MD=0.38, 95%CI 0.28~0.67,P<0.001)及术后1、3、6、12个月的Harris评分上均要优于单纯三枚空心钉组;两组的复位质量为良、术后感染、骨折延迟愈合比较差异无统计学意义。结论:三枚空心钉结合内侧支撑钢板治疗青壮年PauwelsⅢ型股骨颈骨折可以提高骨折复位质量,降低术后并发症发生率,提高患者术后髋关节功能评分,但其手术时间长于单纯空心钉组且术中出血量也多。

Objective: To compare the effectiveness of the medial support plate combined with three cannulated screws versus simple three cannulated screws in treating Pauwels type Ⅲ femoral neck fracture in young adults through Meta-analysis. Methods: A search was conducted across various databases including CNKI, Wanfang, VIP, PubMed, Cochrane Library, and Web of Science(WOS) to find randomized controlled trials, cohort studies, and other literature related to the treatment of Pauwels type Ⅲ femoral neck fracture using medial support plate combined with three cannulated screws or simple three cannulated screws. The search period covered the time from the inception of the database to June 2023. The screening, quality evaluation, data extraction, and other tasks were performed independently by two individuals based on established inclusion criterias. At last, Stata 14 and stata 17 were used for Meta-analysis. Results: Twenty articles were included comprising a total of 1 294 patients. The Meta-analysis showed that the operation time was longer(MD=26.52,95% CI 20.99-31.50, P<0.001) and intraoperative blood loss was more(MD=89.68,95% CI 70.95-107.42,P<0.001) in the medial support plate combined with three cannulated screws group than those in the simple three cannulated screws group. The incidence of reduction quality for acceptable(RR=0.32, 95% CI 0.17-0.58, P<0.001) and poor(RR=0.17, 95% CI 0.06-0.45, P<0.001) was lower than those of the simple three cannulated screws group. The time of healing fractures was significantly reduced(MD=1.05, 95%CI-1.34 –-0.67, P<0.001) in patients in the medial support plate combined with three cannulated screws group. Additionally, the quality of the reduction for perfect(RR=1.57, 95%CI 1.35-1.83, P<0.001) was higher, and the total number of postoperative complications was lower(RR=0.31, 95%CI 0.24-0.40, P<0.001), and the incidence of femoral head necrosis was reduced(RR=0.43, 95%CI 0.08-1.80, P<0.001) in the medial support plate combined with three cannulated screws group. Moreover, the rate of fracture nonunion was lower(MD=0.38, 95%CI 0.28-0.67, P<0.001), and the Harris scores at 1 month, 3 months, 6 months, and 12 months after the operation were better in the medical support plate combined with three cannulated screws group than those of the simple three cannulated screws group. There was no significant difference between the two groups in the reduction quality for good, postoperative infection, and delayed fracture healing. Conclusion: The use of three cannulated screws along with a medial support plate can be effective in treating Pauwels type Ⅲ femoral neck fractures. This method can result in better fracture reduction, fewer postoperative complications, and improved functional scores for patients after operation. However, the operation time is longer and intraoperative blood loss is higher compared to the simple three cannulated screws group.

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