辅助生殖技术助孕多囊卵巢综合征不孕患者无法忍受不确定性影响因素分析-现代医学

辅助生殖技术助孕多囊卵巢综合征不孕患者无法忍受不确定性影响因素分析

单位：空军军医大学第二附属医院妇产科生殖中心, 陕西西安 710032

分类号：R322.6

出版年·卷·期（页码）：2025·44·第六期（935-940）

摘要：

目的： 探讨辅助生殖技术(ART)助孕多囊卵巢综合征(PCOS)不孕患者无法忍受不确定性(IU)状况及其影响因素，为临床心理干预提供指导。方法： 采用便利抽样法，选择2023年5月至2024年5月于本院接受ART助孕的156例PCOS不孕患者为研究对象。使用一般资料调查问卷、简版无法忍受不确定性量表(IUS-12)、感知伴侣回应性量表(PPRS)进行问卷调查。结果： 最终有效回收问卷148份，有效回收率为94.87%。148例ART助孕PCOS不孕患者IUS-12评分为(31.26±6.48)分，处于中等水平。单因素分析显示，不同文化程度、职业状态、家庭月收入、经济负担、有无子女、有无传统生育观念、ART认知状况的PCOS不孕患者IUS-12评分比较，差异有统计学意义(P＜0.05)。Pearson相关分析显示，PPRS得分与IUS-12评分之间存在显著负相关(r=-0.542，P＜0.001)。多元线性回归分析显示，随着经济负担加重(B=5.218，95%CI 3.854～6.582)，患者IU水平显著升高；有传统生育观念的患者IU水平显著高于无传统生育观念的患者(B=4.674，95%CI 3.273～6.075)；了解ART的患者IU水平显著低于不了解ART的患者(B=-3.867，95%CI-5.208～-2.526)；随着感知伴侣回应性水平提升(B=-0.826，95%CI-1.038～-0.614)，患者IU水平显著降低(P＜0.05)。结论： ART助孕PCOS不孕患者IU现状不容乐观，经济负担、有无传统生育观念、ART认知状况、感知伴侣回应性水平均是其影响因素，临床可据此采取针对性干预措施。

Objective: To investigate the status of intolerance of uncertainty(IU) and its influencing factors in infertile polycystic ovary syndrome(PCOS) patients undergoing assisted reproductive technology(ART), providing guidance for clinical psychological interventions. Methods:Using convenience sampling, 156 infertile PCOS patients receiving ART treatment at our hospital from May 2023 to May 2024 were selected. Data were collected using a general information questionnaire, the Intolerance of Uncertainty Scale-12(IUS-12), and the Perceived Partner Responsiveness Scale(PPRS).Results:A total of 148 valid questionnaires were collected(effective response rate: 94.87%). The mean IUS-12 score was 31.26 ±6.48, indicating moderate IU levels. Significant differences in IU scores were observed among patients with different occupational statuses, educational levels, monthly family incomes, financial burdens, presence of children, traditional fertility beliefs, and ART knowledge status(P<0.05). Pearson correlation analysis showed a significant negative correlation between PPRS and IUS-12 scores(r=-0.542, P<0.001). Multiple linear regression analysis revealed that increased financial burden(B=5.218, 95% CI 3.854-6.582), presence of traditional fertility beliefs(B=4.674, 95% CI 3.273-6.075), and lack of ART knowledge(B=-3.867, 95% CI-5.208- -2.526) significantly increased IU levels. Higher perceived partner responsiveness reduced IU levels(B=-0.826, 95% CI -1.038- -0.614, P<0.05). Conclusion: IU levels among ART-treated infertile PCOS patients remain concerning, with financial burden, traditional fertility beliefs, ART knowledge status, and perceived partner responsiveness being key influencing factors, warranting targeted clinical interventions.

参考文献：

[1] WANG Y,FU Y,GHAZI P,et al.Prevalence of intimate partner violence against infertile women in low-income and middle-income countries:a systematic review and meta-analysis[J].Lancet Glob Health,2022,10(6):e820-e830.
[2] 喻亚娜,张苏丽,杨贵芳,等.多囊卵巢综合征的免疫机制及免疫治疗研究进展[J].现代医学,2024,52(6):965-970.
[3] 高丽婷,洪翔,施勇,等.阴道微生态与辅助生殖结局的相关性研究进展[J].东南大学学报(医学版),2023,42(6):932-938.
[4] 张孝东,邓成艳,黄学锋,等.中华医学会生殖医学分会:2019年辅助生殖技术数据报告[J].生殖医学杂志,2022,31(8):1015-1021.
[5] 郑观蕾.农村不孕女性辅助生殖治疗的经济压力与应对策略[J].医学与哲学,2024,45(24):38-43.
[6] 李利娜,孙强,崔春明,等.辅助生殖技术受孕与自然受孕孕妇心理健康状况比较[J].中国实用护理杂志,2022,38(1):40-45.
[7] STEPHENS G C,SARKAR M,LAZARUS M D.A whole lot of uncertainty:a qualitative study exploring clinical medical students' experiences of uncertainty stimuli[J].Med Educ,2022,56(7):736-746.
[8] 姚泥沙,杨寅,舒淑,等.不确定性不耐受对情绪问题的影响 ——应对的中介作用与正念的调节作用[J].北京大学学报(自然科学版),2023,59(2):317-325.
[9] 杨小萍,王慧娟,刘晓慧,等.首发脑卒中患者D型人格与无法忍受不确定性的关系:家庭支持的中介作用[J].中国实用护理杂志,2024,40(7):548-555.
[10] TEEDE H J,MISSO M L,COSTELLO M F,et al.Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome[J].Hum Reprod,2018,33(9):1602-1618.
[11] 陈子江,刘嘉茵,黄荷凤,等.不孕症诊断指南[J].中华妇产科杂志,2019,54(8):505-511.
[12] CARLETON R N,NORTON M A,ASMUNDSON G J.Fearing the unknown:a short version of the intolerance of uncertainty scale[J].J Anxiety Disord,2007,21(1):105-117.
[13] 吴莉娟,王佳宁,齐晓栋.简版无法忍受不确定性量表在中学生中应用的效度和信度[J].中国心理卫生杂志,2016,30(9):700-705.
[14] REIS H T,MANIACI M R,CAPRARIELLO P A,et al.Familiarity does indeed promote attraction in live interaction[J].J Pers Soc Psychol,2011,101(3):557-570.
[15] 杨舒程,王子祥,刘振亮,等.感知伴侣回应性量表中文版的信效度检验[J].中国临床心理学杂志,2019,27(5):950-953.
[16] 白璐,房玉英,贾冬梅,等.接受体外受精胚胎移植助孕女性患者的无法忍受不确定性及相关因素[J].中国心理卫生杂志,2024,38(5):400-406.
[17] JOLINK T A,CHANG Y P,ALGOE S B.Perceived partner responsiveness forecasts behavioral intimacy as measured by affectionate touch[J].Pers Soc Psychol Bull,2022,48(2):203-221.
[18] 孙永红,陈玲,赵翠菊,等.育龄期乳腺癌患者感知伴侣回应性与生育忧虑的关系研究[J].护理管理杂志,2022,22(2):134-138.
[19] 刘媛媛,邓云,刘兰香,等.不孕症女性与配偶生育压力、感知伴侣回应及家庭复原力的关系研究[J].护理学杂志,2024,39(13):1-5.
[20] 付逗,龚甜甜,杨欣,等.武汉市轮转护士职业不确定感现状及影响因素研究[J].职业与健康,2023,39(24):3373-3377.
[21] LI M N,ZHOU B,HU B B.Relationship between income and mental health during the COVID-19 pandemic in china[J].Int J Environ Res Public Health,2022,19(15):8944.
[22] 马丽,施金凤,仇茜.高龄妇女辅助生殖助孕前心理状态及影响因素分析[J].中国计划生育学杂志,2022,30(11):2423-2428.
[23] 杨静薇,邓成艳,黄学锋,等.中华医学会生殖医学分会2018年度辅助生殖技术数据报告[J].生殖医学杂志,2021,30(4):419-425.

服务与反馈：

【文章下载】【发表评论】【查看评论】【加入收藏】

提示：您还未登录，请登录！点此登录