Objective: To explore the effects of computer-assisted cognitive rehabilitation(CACR) combined with physical fitness training on cognitive functions, adaptive behaviors of children with mental retardation(MR). Methods: A total of 90 MR children who received rehabilitation treatment at the Rehabilitation Center of Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University from December 2023 to December 2024 were included. They were divided into the conventional training group(Group A), CACR group(Group B), and CACR combined with physical fitness group(Group C) using a random number table method, with 30 cases in each group. Group A received conventional intervention, Group B received CACR, and Group C received CACR combined with physical fitness training. The Wechsler Intelligence Scale for Children-Fourth Edition(WISC-Ⅳ) scores, Peabody Picture Vocabulary Test(PPVT) scores, children's adaptive behavior indicators, and physical fitness indicators of each group were observed and compared before and after treatment. Results: Before treatment, there were no statistically significant differences in the WISC-Ⅳ scores, PPVT scores, adaptation quotient(ADQ),cognitive factor scores, independence factor scores, social/self-control factor scores, left and right leg support time, walking balance beam time, standing long jump distance, sit-and-reach distance, jumping jacks time, front-and-back clapping time, and shuttle run time among the three groups(all P>0.05). After treatment, the above indicators in the three groups showed a significant time effect(P<0.001), meaning that the scores in each group were significantly improved compared with those before treatment. Both the inter-group effect and interaction effect were statistically significant(all P<0.001). Further inter-group comparison showed that the WISC-Ⅳ scores, PPVT scores, ADQ, independent factor scores, cognitive factor scores, and physical fitness indicators in Group C were better than those in Groups A and B(P<0.05); the social/self-control factor scores in Groups C and B were higher than those in Group A(P<0.05). Conclusion: CACR combined with physical fitness training can help improve cognitive function, adaptive ability and physical fitness of MR children, and has clinical application value. |
[1] BOBBETTE N,OUELLETTE-KUNTZ H,TRANMER J,et al.Adults with intellectual and developmental disabilities and interprofessional,team-based primary health care:a scoping review[J].JBI Evid Synth,2020,18(7):1470-1514.
[2] SCHALOCK R L,LUCKASSON R,TASSÉ M J.The contemporary view of intellectual and developmental disabilities:implications for psychologists[J].Psicothema,2019,31(3):223-228.
[3] TOTSIKA V,LIEW A,ABSOUD M,et al.Mental health problems in children with intellectual disability[J].Lancet Child Adolesc Health,2022,6(6):432-444.
[4] KURTZ P F,LEONI M,HAGOPIAN L P.Behavioral approaches to assessment and early intervention for severe problem behavior in intellectual and developmental disabilities[J].Pediatr Clin North Am,2020,67(3):499-511.
[5] 李旭利.感觉统合训练治疗精神运动发育迟缓患儿的效果[J].中外医学研究,2021,19(35):1-4.
[6] NIE P,LIU F,LIN S,et al.The effects of computer-assisted cognitive rehabilitation on cognitive impairment after stroke:a systematic review and meta-analysis[J].J Clin Nurs,2022,31(9-10):1136-1148.
[7] 周秀秀.中国中老年人身体活动与认知功能的关系研究[D].武汉:华中科技大学,2021.
[8] TASSÉ M J,LUCKASSON R,NYGREN M.AAIDD proposed recommendations for ICD-11 and the condition previously known as mental retardation[J].Intellect Dev Disabil,2013,51(2):127-131.
[9] 张慧敏.韦氏儿童智力量表第四版(WISC-Ⅳ)在癫痫儿童认知评估中的应用[D].合肥:安徽医科大学,2019.
[10] ESNAFOGLU E,ADIGüZEL Ö.Association of BDNF levels with IQ:comparison of S100B and BDNF levels in typically developing children and subjects with neurologically normal nonsyndromic intellectual disability[J].J Intellect Disabil Res,2021,65(12):1073-1084.
[11] LEVY A M,GOMEZ-PUERTAS P,TüMER Z.Neurodevelopmental disorders associated with PSD-95 and its interaction partners[J].Int J Mol Sci,2022,23(8):4390.
[12] SALPIETRO V,DIXON C L,GUO H,et al.AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders[J].Nat Commun,2019,10(1):3094.
[13] 傅萍,阙秀琴,吴强.电针听会、本神穴联合康复训练治疗精神发育迟滞患儿的临床效果[J].中国当代医药,2024,31(32):39-43.
[14] 罗维.rTMS联合认知训练对精神发育迟缓患儿智能及社会适应能力的影响[J].云南医药,2021,42(2):133-135.
[15] 陈雅恒,杜超,姜剑.精神运动发育迟缓儿童行三级康复治疗对其运动功能、神经功能缺损及生存质量的影响分析[J].辽宁医学杂志,2020,34(1):44-46.
[16] HO H Y,CHEN M D,TSAI C C,et al.Effects of computerized cognitive training on cognitive function,activity,and participation in individuals with stroke:a randomized controlled trial[J].NeuroRehabilitation,2022,51(1):79-89.
[17] AMORÓS-AGUILAR L,RODRÍGUEZ-QUIROGA E,SÁNCHEZ-SANTOLAYA S,et al.Effects of combined interventions with aerobic physical exercise and cognitive training on cognitive function in stroke patients:a systematic review[J].Brain Sci,2021,11(4):473.
[18] 何友泽.基于脑网络结构-功能耦合及拓扑属性探讨计算机辅助认知训练对MCI患者的作用机制[D].福州:福建中医药大学,2022.
[19] FERRER-URIS B,RAMOS M A,BUSQUETS A,et al.Can exercise shape your brain?A review of aerobic exercise effects on cognitive function and neuro-physiological underpinning mechanisms[J].AIMS Neurosci,2022,9(2):150-174.
[20] GHODRATI N,HAGHIGHI A H,KAKHAK S A H,et al.Effect of combined exercise training on physical and cognitive function in women with type 2 diabetes[J].Can J Diabetes,2023,47(2):162-170.
[21] MAURUS I,HASAN A,RÖH A,et al.Neurobiological effects of aerobic exercise,with a focus on patients with schizophrenia[J].Eur Arch Psychiatry Clin Neurosci,2019,269(5):499-515.
[22] ERICKSON K I,HILLMAN C,STILLMAN C M,et al.Physical activity,cognition,and brain outcomes:a review of the 2018 physical activity guidelines[J].Med Sci Sports Exerc,2019,51(6):1242-1251.
[23] GUSATOVIC J,GRAMKOW M H,HASSELBALCH S G,et al.Effects of aerobic exercise on event-related potentials related to cognitive performance:a systematic review[J].PeerJ,2022,10:e13604.
[24] 陈云杰,王玉俊.视频游戏联合康复治疗对精神发育迟滞患儿智能发育和运动能力的影响[J].当代医学,2020,26(28):80-83.
[25] 俞鑫璐,李鑫,杨婷婷,等.体适能训练对全面性发育迟缓儿童社会适应行为的影响[J].中国儿童保健杂志,2024,32(5):496-501.
[26] LIMAYE N S,CARVALHO L B,KRAMER S.Effects of aerobic exercise on serum biomarkers of neuroplasticity and brain repair in stroke:a systematic review[J].Arch Phys Med Rehabil,2021,102(8):1633-1644.
[27] PALMER J A,WHITAKER A A,PAYNE A M,et al.Aerobic exercise improves cortical inhibitory function after stroke:a preliminary investigation[J].J Neurol Phys Ther,2024,48(2):83-93.
[28] FU T,ZHANG D,WANG W,et al.Functional training focused on motor development enhances gross motor,physical fitness,and sensory integration in 5-6-year-old healthy Chinese children[J].Front Pediatr,2022,10:936799.
[29] LI J,HUANG Z,SI W,et al.The effects of physical activity on positive emotions in children and adolescents:a systematic review and meta-analysis[J].Int J Environ Res Public Health,2022,19(21):14185.
[30] KOH S H.Analyzing the influence of physical exercise interventions on social skills in children with autism spectrum disorder:insights from meta-analysis[J].Front Psychol,2024,15:1399902.
[31] ROBLEDO-CASTRO C,LERMA-CASTAÑO P R,BONILLA-SANTOS G.Effect of cognitive training programs based on computer systems on executive functions in children with ADHD:a systematic review[J].J Atten Disord,2023,27(13):1467-1487.
[32] ZHAO X,HUANG X,ZOU B,et al.Compared to exercise,the effects of exercise combined with cognitive training in people with mild cognitive impairment:a network meta-analysis[J].Aging Ment Health,2025,29(1):154-166.
[33] MENG Q,YIN H,WANG S,et al.The effect of combined cognitive intervention and physical exercise on cognitive function in older adults with mild cognitive impairment:a meta-analysis of randomized controlled trials[J].Aging Clin Exp Res,2022,34(2):261-276.
[34] 谢荣桂,邓贵玉,裴景茹,等.不同运动方式对冠心病患者心肺储备功能和运动耐力影响的网状Meta分析[J].现代医学,2024,52(11):1639-1651.
[35] 程敏,甘皓月,宁莉萍,等.不同运动方式对老年衰弱患者影响的网状Meta分析[J].现代医学,2024,52(4):551-559.
[36] WAN Y T,CHIANG C S,CHEN S C,et al.The effectiveness of the computerized visual perceptual training program on individuals with down syndrome:an fMRI study[J].Res Dev Disabil,2017,66:1-15. |