幽门螺杆菌感染与心律失常相关性研究-现代医学

幽门螺杆菌感染与心律失常相关性研究

单位：1. 东部战区空军医院心内科, 江苏南京 210000;
2. 南京同仁医院心内科, 江苏南京 210007

分类号：R541.7

出版年·卷·期（页码）：2025·53·第十期（1584-1588）

摘要：

目的：探讨幽门螺旋杆菌(Hp)感染与心律失常的相关性。方法：回顾性研究分析2020年1月至2024年6月因心律失常就诊患者的相关资料。患者均入院进行了动态心电图(Holter)、心脏彩超检查及Hp等检测。Logistic回归分析Hp感染与心律失常的关系。结果：共纳入354例患者，根据有无感染Hp分为Hp阳性组与Hp阴性组，两组人群性别、年龄、体质量指数(BMI)、基础心脏病史、饮酒史、吸烟史、糖尿病病史、高血压病史等比较差异无统计学意义(P>0.05)。Hp阳性组房性早搏和心房颤动(AF)组的OR值在多变量调整后分别为2.90(95% CI 1.60~5.25,P<0.001)和10.67(95% CI 3.21~35.49,P<0.001)。结论：Hp感染对房性早搏及AF有显著影响。

Objective: To explore the correlation between Helicobacter pylori(Hp) infection and arrhythmia. Methods: A retrospective study was conducted on patients who visited the hospital due to arrhythmias from January 2020 to June 2024. All patients underwent ambulatory electrocardiography(Holter), echocardiography, and detection of indicators such as Hp. Logistic regression was used to analyze the relationship between Hp infection and arrhythmia. Results: A total of 354 patients were enrolled and divided into the Hp-positive group and Hp-negative group based on the presence or absence of Hp infection. There were no significant differences between the two groups in terms of gender, age, body mass index(BMI), history of underlying heart disease, drinking history, smoking history, and history of diabetes or hypertension. After multivariate adjustment, the odds ratios(ORs) of atrial premature beats and atrial fibrillation(AF) in the Hp-positive group were 2.90(95% CI 1.60-5.25, P<0.001) and 10.67(95% CI 3.21-35.49, P<0.001) respectively. Conclusion: Hp infection has a significant impact on atrial premature beats and AF.

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