高血压患者饮酒行为及睡眠质量与血压控制的关联性研究-现代医学

高血压患者饮酒行为及睡眠质量与血压控制的关联性研究

单位：1. 南京江北新区公共卫生服务中心疾病预防控制所, 江苏南京 210044;
2. 南京疾病预防控制中心慢性非传染性疾病防制科, 江苏南京 210009

分类号：R181.3

出版年·卷·期（页码）：2025·53·第十二期（1914-1919）

摘要：

目的：探讨成年高血压患者饮酒行为、睡眠质量及其交互作用对血压控制的影响。方法：基于2021年6月至11月南京江北新区慢性病危险因素流行病学调查数据，选取其中的高血压患者作为研究对象。通过多因素非条件Logistic回归模型分析饮酒行为和睡眠质量对血压控制的独立效应及其交互作用。结果：本研究共纳入4 138例高血压患者，血压控制率为26.7%。调整年龄、性别、文化程度、身体活动水平、身体质量指数(BMI)、吸烟行为、药物治疗、糖尿病、血脂异常患病情况等因素后，与不饮酒且睡眠质量优良者相比，不饮酒且睡眠质量差(OR=0.723，95%CI 0.593~0.882)、饮酒且睡眠质量优良(OR=0.678，95%CI 0.481~0.955)以及饮酒且睡眠质量差(OR=0.539，95% CI 0.415~0.699)的居民高血压控制可能性明显降低。交互作用分析显示，饮酒行为与睡眠质量之间未发现相乘或相加的交互作用。结论：饮酒行为和睡眠质量差均不利于高血压患者的血压控制，尚未发现两者间存在交互作用。

Objective: To investigate the effects of drinking behavior, sleep quality, and their interaction on blood pressure(BP) control among adult hypertensive patients. Methods: This study analyzed data from hypertensive patients obtained from the Chronic Disease Risk Factor Surveillance database in Jiangbei New District, Nanjing between June and November 2021. A multivariate unconditional Logistic regression model was used to analyze the independent and interaction effects of drinking behavior and sleep quality on BP control. Results: A total of 4 138 hypertensive patients were included in this study, and the BP control rate was 26.7%. After adjusting for age, sex, education level, physical activity, body mass index(BMI), smoking behavior, drug treatment, diabetes and dyslipidemia, significantly lower odds of achieving BP control were observed in people with non-drinking and poor sleep quality(OR=0.723, 95%CI=0.593~0.882), drinking and well sleep quality(OR=0.678, 95%CI=0.481-~0.955), drinking and poor sleep quality(OR=0.539，95%CI=0.415~0.699) than people with non-drinking and well sleep quality. And interaction analysis revealed that no multiplicative or additive interaction was found between drinking behavior and sleep quality. Conclusion: Both drinking behavior and poor sleep quality negatively impact BP control in hypertensive adults, and no interaction has been found between these two factors.

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