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IL-35与人类疾病关系的研究进展
作者:王幸  张祥贵 
单位:遵义医学院第五附属(珠海)医院 肾内科, 广东 珠海 519000
关键词:白细胞介素35 Treg细胞 自身免疫 炎症 文献综述 
分类号:R392.11
出版年·卷·期(页码):2019·47·第一期(109-112)
摘要:

白细胞介素35(interleukin35,IL-35)是IL-12家族的新成员,是一种新型抗炎因子,不仅促进调节性T细胞(regulatory T-cell,Treg)的增殖,还可抑制辅助性T细胞17(Thelper cell 17,Th17)的分化及IL-17的分泌,从而发挥免疫抑制作用。目前研究认为,IL-35广泛参与人类各系统疾病的发生、发展,是目前新的研究热点。现将近年来有关IL-35与各系统疾病的关系作一综述。

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